The purpose of our study is to investigate the effects of the different dosage of memantine for the treatment of Critical Illness Polyneuropathy (CIP) in rats that have surgically induced sepsis, by using electromyography (EMG) signs, such as amplitude and duration of compound muscle action potentials (CMAP), distal latency, and by using levels of plasma tumor necrosis factor (TNF)-α and lipid peroxides (malondialdehyde, (MDA)).
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