Letter To The Editor

Vol. 53 No. 2 (2015): Neuropsychiatric Investigation

The evaluation of the therapeutic effect of memantine in sepsis induced critical illness polyneuropathy

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Volkan Solmaz
Bilge Piri Çınar
Yiğit Uyanıkgil
Türker Çavuşoğlu
Gönül Peker
Oytun Erbaş

Abstract

The purpose of our study is to investigate the effects of the different dosage of memantine for the treatment of Critical Illness Polyneuropathy (CIP) in rats that have surgically induced sepsis, by using electromyography (EMG) signs, such as amplitude and duration of compound muscle action potentials (CMAP), distal latency, and by using levels of plasma tumor necrosis factor (TNF)-α and lipid peroxides (malondialdehyde, (MDA)).

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